B4

Leukotriene B4 and asthma.

Murine Glomerular Leukotriene B4 Synthesis

Leukotriene (LT) B4 is an important pro-inflammatory autocoid. In order to investigate the potential role of this eicosanoid in renal inflammation, in this study we determined the capability of glomeruli to synthesize this mediator. Glomeruli were able to synthesize LTB4 when provided with exogenous substrate in a dose-dependent fashion in the presence of ionophore A23187. Ionophore, although b...

hep-th/9607112 USC-96/HEP-B4

The representation theory of the maximally extended superalgebra with 32 fermionic and 528 bosonic generators is developed in order to investigate non-perturbative properties of the democratic secret theory behind strings and other p-branes. The presence of Lorentz non-singlet central extensions is emphasized, their role for understanding up to 13 hidden dimensions and their physical interpreta...

A fatal case of coxsackievirus B4 meningoencephalitis.

BACKGROUND Coxsackieviruses and echoviruses are common causes of aseptic meningitis, but they rarely cause life-threatening illness. We report a fatal case of coxsackievirus B4 meningoencephalitis in a woman who developed extrapyramidal symptoms suggestive of encephalitis lethargica. The exact causative agent of encephalitis lethargica has rarely been found, but most cases of the syndrome are a...

A Second Leukotriene B4 Receptor, Blt2

Leukotriene B(4) (LTB(4)) is a potent chemoattractant and activator of both granulocytes and macrophages. The actions of LTB(4) appear to be mediated by a specific G protein-coupled receptor (GPCR) BLT1, originally termed BLT (Yokomizo, T., T. Izumi, K. Chang, Y. Takuwa, and T. Shimizu. 1997. Nature. 387:620-624). Here, we report the molecular cloning of a novel GPCR for LTB(4), designated BLT2...